MONOSİT SAYISININ HDL-KOLESTEROLE ORANI FONKSİYONEL ADRENAL TÜMÖRLÜ HASTALARDA YENİ BİR KARDİYOMETABOLİK BELİRTEÇ OLABİLİR

Adrenal Function in Females with Low Plasma HDL-C Due to Mutations in ABCA1 and LCAT

INTRODUCTION Adrenal steroidogenesis is essential for human survival and depends on the availability of the precursor cholesterol. Male subjects with low plasma levels of high density lipoprotein (HDL) cholesterol are characterized by decreased adrenal function. Whether this is also the case in female subjects with low plasma HDL-C levels is unresolved to date. FINDINGS 15 female ATP binding ...

HDL is redundant for adrenal steroidogenesis in LDLR knockout mice with a human-like lipoprotein profile.

The contribution of HDL to adrenal steroidogenesis appears to be different between mice and humans. In the current study, we tested the hypothesis that a difference in lipoprotein profile may be the underlying cause. Hereto, we determined the impact of HDL deficiency on the adrenal glucocorticoid output in genetically modified mice with a human-like lipoprotein profile. Genetic deletion of APOA...

A Recursive Dynamic Computable General Equilibrium Model For Agricultural Policy Analysis in Spain ( ORANI - DYN ) . Part II : Modifications to the Standard ORANI - G model framework

Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112

RATIONALE CSL112, human apolipoprotein A-I (apoA-I) reconstituted with phosphatidylcholine, is known to cause a dramatic rise in small high-density lipoprotein (HDL). OBJECTIVE To explore the mechanisms by which the formation of small HDL particles is induced by CSL112. METHODS AND RESULTS Infusion of CSL112 into humans caused elevation of 2 small diameter HDL fractions and 1 large diameter...

Mitral Darlığı Olan Hastalarda Atriyal Elektiriksel ve Elektromekanik Özellikler ÖZET

Introduction: AF in patients with mitral stenosis (MS) causes significant morbidity and mortality. PMBV, which is a treatment of choice for patients with MS, is a highly successful procedure that provides significant improvement in symptoms and echocardiographic parameters. In this study we aimed to demonstrate the probable effects of PMBV on novel echocardiographic and electrocardiographic par...